Hyphema is defined as the presence of blood in the anterior chamber. Various causes include eye trauma, systemic hypertension, and chronic inflammation (uveitis), to name a few. Initially, a complete ophthalmic examination is necessary to determine if the cause is primary (trauma), or secondary (systemic disease). A complete workup hemogram, physical examination, urinalysis) maybe warranted. Blood pressure measurement maybe necessary in animals that present with retinal detachment, hemorrhage or hyphema. Treatment of hyphema usually requires both topical and oral anti-inflammatory drugs. If a secondary glaucoma (elevated intraocular pressure) develops, a topical and/or oral antiglaucoma therapy will be necessary.